Case Studies

Our case studies below describe occasions when Yellow Card reports have directly contributed to patient safety. 

When a new safety issue is identified following a Yellow Card report: 

• relevant warnings will be added to the product information 

• advice on how the product should be used may change 

• warnings may be given to groups of patients, healthcare professionals or users of the product 

Often, safety issues are not linked to a specific medicine or medical device until they are reported to the Yellow Card scheme. Information from Yellow Card reports is considered alongside other safety information. 

Reporting can make a big difference in keeping the public safe. Find out more about the Yellow Card scheme, including what happens when you submit a report.

About a medicine

• Charcoal and drug interaction

• Eye drops and HIV medication reaction

• Ranitidine and breast disorders

• Rivaroxaban (Xarelto ▼) drug administration error

About a medical device

• Blood gas analyser

• Skin wipes allergic reaction

• COPD medicine and choking

Non-prescription product reported

• Bonjela gel and swollen tongue

• Corn plasters and skin ulceration

• Gaviscon Infant and constipation

Patient reported

• Contraception Yasmin and hair loss

• Labetalol and nipple pain

• Perindopril and Raynaud's phenomenon

• Sayana and muscle loss

Healthcare professional reported

• Nexplanon contraceptive implants

• Phacoemulsification handpieces cataract surgery

• Posaconazole medication error

Prescription-only product reported

• HIV medicine and Fluticasone reaction

• Phenytoin and purple glove syndrome

• Steroids and red skin syndrome